Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ASXL1 All Species: 13.94
Human Site: T683 Identified Species: 34.07
UniProt: Q8IXJ9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IXJ9 NP_056153.2 1541 165432 T683 E P R G G P S T P G K C T S D
Chimpanzee Pan troglodytes XP_001156134 1531 163916 T673 E P R G G P S T P G K C T S D
Rhesus Macaque Macaca mulatta XP_001108038 1589 170584 T731 E P R G G P S T P G K C T S D
Dog Lupus familis XP_853069 2156 231578 T1058 E T K I E G S T G V I I V N P
Cat Felis silvestris
Mouse Mus musculus P59598 1514 162656 T680 E P R G A P S T S G E S A S D
Rat Rattus norvegicus XP_002729264 1286 136594 D466 N G E H T Q A D A A M V R A K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515168 1882 199357 A838 L Q Q S L G A A K L Q E S A T
Chicken Gallus gallus Q5ZM88 1412 148651 E592 G K K P R I A E K C Q Q Q Q P
Frog Xenopus laevis NP_001086579 738 82633
Zebra Danio Brachydanio rerio XP_001341242 1619 172271 D727 G R R G G R V D L E E Q E S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.4 91.1 21.7 N.A. 74 59 N.A. 28.1 26.7 29.2 27.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.4 93.5 36 N.A. 81.1 66.3 N.A. 41.7 41.9 36.5 41.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 20 N.A. 66.6 0 N.A. 0 0 0 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 33.3 N.A. 73.3 13.3 N.A. 33.3 20 0 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 30 10 10 10 0 0 10 20 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 0 30 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 20 0 0 0 0 0 0 40 % D
% Glu: 50 0 10 0 10 0 0 10 0 10 20 10 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 20 10 0 50 40 20 0 0 10 40 0 0 0 0 0 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 10 0 0 0 0 10 10 0 0 0 % I
% Lys: 0 10 20 0 0 0 0 0 20 0 30 0 0 0 10 % K
% Leu: 10 0 0 0 10 0 0 0 10 10 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 40 0 10 0 40 0 0 30 0 0 0 0 0 30 % P
% Gln: 0 10 10 0 0 10 0 0 0 0 20 20 10 10 0 % Q
% Arg: 0 10 50 0 10 10 0 0 0 0 0 0 10 0 0 % R
% Ser: 0 0 0 10 0 0 50 0 10 0 0 10 10 50 0 % S
% Thr: 0 10 0 0 10 0 0 50 0 0 0 0 30 0 10 % T
% Val: 0 0 0 0 0 0 10 0 0 10 0 10 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _